BioavailabilityDesign (BD) Expert predicts the time profiles of oral drug absorption based on the fully mechanistic theoretical framework (the GUT framework). Gastrointestinal (GI) physiology, the dissolution and the intestinal membrane permeation of a drug in the GI tract are dynamically simulated. The GUT framework has been published in the literature (i.e., no black-box) and independently validated by third parties.
BioavailabilityDesignMini is software that predicts the oral absorption rate of a drug from in vitro data. Calculate the oral absorption rate (Fa: fraction of a dose absorbed) by approximate analytical solution (Fa formula). It was developed to provide the theory on oral absorption rate prediction developed by Dr. Kiyohiko Sugano (Professor of Ritsumeikan University Department of Pharmacy, former Pfizer Associate research fellow), the foremost expert in this field, as software
GIS-α in-vivo predictive dissolution tester|
Jointly developed by JMC (Japan Machinery Company) and HITZ (Hitachi Zosen corporation). Innovative Dissolution Tester widely experimented and evaluated at University of Michigan. Transfer model simulating stomach->duodenum->jejunum->ileum and also biphasic system.